Atrial fibrillation
Conditions
Interventions
Group A:Intervention of left atrium only: minimally invasive surgery performed left atrial ring pulmonary vein isolation + posterior wall box + left atrial appendage ligation, and then verification an
Group B:Left and right atrium intervention: left and right atrium isolation, left atrial ring pulmonary vein electrical isolation + posterior wall box + left atrial appendage ligation + right atrial s
Group C:Intervention of left atrium only: with the aid of three-dimensional mapping system, the left atrium was firstly mapped with matrix (voltage), and then ablation was guided according to the mapp
Group D:Left and right atrium intervention at the same time: with the assistance of three-dimensional mapping system of internal medicine, the matrix (voltage) mapping of left atrium and right atrium
Group E:Radiofrequency catheter ablation assisted by three-dimensional mapping system
Sponsors
The Ninth People's Hospital Affiliated to Medical School of Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) The age was less than 75 years old and over 18 years old; 2) The duration of persistent AF was more than 1 week; 3) Long term persistent atrial fibrillation, atrial fibrillation time more than 1 year; 4) The diameter of left atrium was less than 60mm; 5) Cardiac function was nyhai-ii, and EF was more than 40%; 6) One month after stroke, the patient's muscle strength was above grade 4, and his mind was clear; 7) The researcher agreed to participate in the clinical trial and sign the informed consent, and agreed to conduct follow-up evaluation according to the requirements of the validation protocol.
Exclusion criteria
Exclusion criteria: 1) The atrial fibrillation caused by hyperthyroidism was before the hyperthyroidism was controlled; 2) Atrial fibrillation caused by rheumatic valvular disease; 3) Atrial fibrillation caused by congenital heart disease; 4) Patients with cor pulmonale and elevated pulmonary artery pressure had atrial fibrillation; 5) Patients with cardiomyopathy complicated with atrial fibrillation; 6) Acute or severe systemic infection; 7) Patients with previous open chest surgery such as CABG and valve replacement. 8) Patients with obvious bleeding tendency and hematological diseases; 9) Patients with aortic dissection or aortic aneurysm; 10) Patients with malignant tumor and end-stage disease; 11) Patients with any other conditions that the researchers consider unsuitable to participate in this trial; 12) From the perspective of medical ethics, researchers consider it necessary to terminate the study of patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate; | — |
Countries
China
Contacts
Public ContactZhang Qingyong
The Ninth People's Hospital Affiliated to Medical School of Shanghai Jiaotong University
Outcome results
None listed