Proximal hypospadias
Conditions
Interventions
1:Androgen therapy
two:None androgen therapy
Sponsors
Shanghai Children's Hospital
Eligibility
Sex/Gender
Male
Age
No minimum to 5 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for proximal hypospadias: (1) penis length 45 degrees; (3) penile head width < 0.6cm. 2. No complicated diseases of heart, brain, liver, kidney or other important organs; 3. No intellectual problems, no diseases of the blood, immune system or endocrine system; 4. To have a full understanding of the purpose, value and significance of this study as well as possible dangerous situations, and to sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have undergone urethral reconstruction or circumcision; 2. Combined with other endocrine axis abnormalities, such as adrenal diseases (CAH, 17 enhancement enzyme deficiency, etc.) and pituitary dysfunction; 3. With known syndromal hypospadias, or a syndrome not clearly diagnosed but combined with multiple organ malformations in addition to hypospadias; 4. Patients who have received hormone therapy; 5. Karyotype was 46, XX.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate after 6 months of surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of penis;width of penile head;Sex hormone levels;psychological states; | — |
Countries
China
Contacts
Public ContactPin Li
Shanghai Children's Hospital
Outcome results
None listed