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The significance of peripheral blood MMP-7 examination combined with liver ultrasound in the staging of liver fibrosis after liver transplantation in children

The significance of peripheral blood MMP-7 examination combined with liver ultrasound in the staging of liver fibrosis after liver transplantation in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036611
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PediatricLiver Transplantation

Interventions

liver&#32
ultrasound
combined&#32
with&#32
Gold Standard:Pathologic diagnosis
Index test:peripheral&#32
blood&#32
MMP-7&#32
examination&#32

Sponsors

Department of General Surgery, Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: 1. Aged < 14 years; 2. Liver transplantation was performed in our hospital; 3. Complete clinical data; 4. Agree and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Combined with other organ failure, severe pulmonary hypertension and acute respiratory distress syndrome; 2. Aortic stenosis with severe cardiac insufficiency, severe valvular heart disease and advanced cardiomyopathy; 3. Severe systemic infection.

Design outcomes

Primary

MeasureTime frame
matrix metalloproteinase7;SEN, SPE, ACC, AUC of ROC;—

Countries

China

Contacts

Public ContactShen Conghuan

Huashan Hospital, Fudan University

sch46@126.com+86 13916719187

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026