Cognitive impairment
Conditions
Interventions
Experimental group:TDCS stimulates the left prefrontal lobe
control group:Sham stimulation of left prefrontal lobe
Sponsors
Department of Neurology, the First Affiliated Hospital of the Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 55 to 85 years; 2. Those diagnosed as early AD met CCMD-3, ad diagnostic criteria; 3. Cooperate with the clinical trial and sign the informed consent form; 4. Patients with denture and pacemaker were excluded; 5. According to the classification standard of dementia, the patients were diagnosed as suspicious and mild dementia according to the CDR grading standard (0.5-1.0).
Exclusion criteria
Exclusion criteria: 1. Sudden and apoplectic onset; 2. Local neurological signs (hemiplegia, sensory disturbance and visual field defect) occurred in the early stage of the disease, or epilepsy or abnormal gait occurred in the early stage of the disease; 3. Dementia and mental illness caused by systemic diseases (depression, schizophrenia, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE;fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Moca;ADL;HRQoL; | — |
Countries
China
Contacts
Public ContactJue Wang
College of Life Science and Technology, Xi'an Jiaotong University
Outcome results
None listed