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ß-hydroxy-ß-methylbutyrate supplementation for the prevention of sarcopenia in Lymphoma patients: a randomized controlled trial

ß-hydroxy-ß-methylbutyrate supplementation for the prevention of sarcopenia in Lymphoma patients: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036602
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma

Interventions

Sponsors

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years and <= 75 years, regardless of gender; 2. Primary lymphoma diagnosed by histology/cytology and imaging (including diffuse large B cell lymphoma, peripheral T cell lymphoma, NK/T cell lymphoma); 3. At least one measurable or objectively evaluable lesion on a PET/CT or CT/MRI examination; 4. Patients who can receive chemotherapy treatment.

Exclusion criteria

Exclusion criteria: 1. Supplement HMB in the short or long term; 2. Severe infection or other diseases requiring ICU treatment; 3. Poor compliance, unable to strictly follow the doctor's orders; 4. Severe renal insufficiency People who need to limit protein intake; 5. Cognitive disorders; 6. Serious mental illness.

Design outcomes

Primary

MeasureTime frame
Skeletal muscle mass;weight;Muscle strength;

Secondary

MeasureTime frame
Adverse reaction;Incidence of sarcopenia;Completion rate of chemotherapy;

Countries

China

Contacts

Public ContactJiang Wu

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

wujiang@xinhuamed.com.cn+86 18221068850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026