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A randomized controlled clinical study on the efficacy and safety of PPOS and antagonist stimulation protocol on ovarian high response infertile women undergoing IVF / ICSI

A randomized controlled clinical study on the efficacy and safety of PPOS and antagonist stimulation protocol on ovarian high response infertile women undergoing IVF / ICSI

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036593
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility IVF stimulation

Interventions

PPOS Group:Progestrone primed ovarian stimulation
Antagonist Group:Antagonist stimulation protocol

Sponsors

Ninth People's Hospital affiliated Shanghai Jiaotong University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 35 Years

Inclusion criteria

Inclusion criteria: (1) The age of the patients was 25-35 years old; (2) basic follicle stimulating hormone (bFSH) 12 ~ 14mm were detected during cos; (5) no uterine and ovarian lesions; bilateral ovaries existed; (6) tubal or male infertility; the indications of IVF / ICSI were met; (7) The first cycle of IVF treatment, no previous IVF treatment history; (8) frozen embryo transfer in all the next month; (9) 18 = BMI = 28KG / m2.

Exclusion criteria

Exclusion criteria: (1) Patients with endometriosis; (2) uterine malformation or endometrial organic lesions; bilateral hydrosalpinx, etc.; (3) history of recurrent abortion; (4) combined with other internal and external diseases affecting endocrine; (5) patients with sperm assisted pregnancy

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate;Cumulative pregnancy rate;

Countries

China

Contacts

Public ContactWang Yao

Ninth People's Hospital affiliated Shanghai Jiaotong University, School of Medicine

drwangyao@163.com+86 13918525522

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026