thyroid associated ophthalmopathy
Conditions
Interventions
Gold Standard:1. Meet two or more of the following three items:
(1) History of abnormal thyroid function
Criteria for diagnosis of Tao were as follows
(2)At least one typical eye symptom of eyelid retraction, exophthalmos, and ocular motility disorders
(3)Imaging evidence of extraocular muscle involvement.
Index test:Artificial 
intelligence 
model 
portraits.
Sponsors
The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) 18-60 years old, male or female; (2) The diagnosis of Tao (with detailed indicators attached); (3) Tao was in moderate to severe active stage (detailed indicators attached); (4) Hormone therapy is proposed.
Exclusion criteria
Exclusion criteria: (1) Severe heart, liver and kidney dysfunction; diabetes, uncontrolled hypertension, mental illness; SLE, RA and other autoimmune diseases; tuberculosis, HIV infection or AIDS patients; glucocorticoid allergy; pregnant women or breast-feeding; hepatitis vaccination within one month before enrollment; (2) He had received hormonal shock therapy, received systemic immunotherapy, including oral or intravenous corticosteroids, various immunosuppressive agents, Tao related targeted drugs, etc; (3) Orbital radiotherapy and eye surgery were performed within 1 month; (4) Compression optic neuropathy ( orbital imaging showed that the extraocular muscles compressed the optic nerve at the orbital apex, and the patient complained that the visual acuity decreased after the onset of the disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectivity of hormone treatment;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactXuefei Song
The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed