Biliary Tract Cancer
Conditions
Interventions
Gold Standard:Pathological and imaging diagnosis of advanced stage (TNM stage III/IV) and distant metastasis of biliary tract cancer
Index test:HSPG-based 
and 
score 
for 
of 
cancer
Sponsors
Third Affiliated Hospital, also called Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with biliary tract cancer diagnosed by imaging and serology after multidisciplinary discussion, have completed clinical tumor staging and metastasis assessment, and are ready to undergo surgical resection, surgical biopsy, or puncture biopsy. There has been no surgery, radiotherapy, cheomtherapy, or other anti-tumor treatments in the past 3 months. 2. Age from 18 to 70 years old; 3. There are measurable or evaluable tumor lesions by CT or MRI (according to RECIST 1.1 standard); 4. KPS score is greater than 60; 5. Good blood function: hemoglobin =8g/dL, absolute neutrophil count =1.5×109/L, platelet count =100×109/L; 6. Good liver and kidney function reserve: Child-Pugh class A liver function, creatinine clearance rate> 60 ml/min; creatinine <120 µmol/L; 7. No heart failure, no uncontrollable chest pain; no myocardial infarction or cerebral infarction occurred in the 12 months before the start of the study; 8. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from other malignant tumors in the past; 2. Active infection period or other serious infections that may interfere with the test results of this project; 3. Patients with severe anemia or other organ insufficiency; 4. Pregnant or breastfeeding women; 5. Individuals undergoing correction monitoring or supervision; 6. Other conditions that may interfere with the test results of this item.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the ROC curve;SEN, SPE, ACC; | — |
Countries
China
Contacts
Public ContactYI Bin
The Third Affilliated Hospital, The Second Military Medical University
Outcome results
None listed