severe acute cholangitis
Conditions
Interventions
Gold Standard:Clinical outcome
Index test:A 
prediction 
model 
based 
on 
in 
the 
cholangitis.
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients with acute cholangitis, diagnostic criteria: 1. Systemic inflammation: (1) Fever and/or shaking chills; (2) Laboratory data: evidence of inflammatory response 2. Cholestasis: (1) Jaundice; (2) Laboratory data: abnormal liver function tests; 3. Imaging: (1) Biliary dilatation; (2) Evidence of the etiology on imaging (stricture, stone, stent etc.); Definite diagnosis: one item in 1, one item in 2 and one item in 3.
Exclusion criteria
Exclusion criteria: 1. Patients with liver cirrhosis; 2. Patients in chemotherapy; 3. Patients taking anticoagulants; 4. Patients with renal failure; 5. Patients with respiratory failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NLR;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP;total bilirubin;AST;White blood cell count;D-Dimer;Blood lipid routine;platelet count; | — |
Countries
China
Contacts
Public ContactYinshi Huang
Department of Gastroenterology, Shanghai General Hospital
Outcome results
None listed