Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Ages between 20 to 70, regardless of gender; 2. The primary liver tumor can be resected. Tumors are far from the first, second, and third hepatic portals. Tumors are mainly located in segments II, III, IVb, V, VI, and VIII of the liver. Diameter of the tumors are less than 5cm. 3. Preoperative evaluation of patients with a high risk of MVI (Feng Shen, et al. JAMA Surg, 2016); 4. Liver function Child A, kidney function and cardiopulmonary function are basically normal. Hb >= 90g/L, white blood cell >= 3.0 x 10^9/L, neutrophil count >= 1.5 x 10^9/L, platelet count >= 60 x 10^9/L; 5. No pregnancy, no HCV, HIV or syphilis infection. Patients can understand the situation of this study and have signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Those who have received chemotherapy, radiotherapy, biological therapy, or other drugs before joining the group; 2) Tumor diameter > 5cm; 3) The tumor has metastasized to other organs, such as lung, brain, bone, etc. 4) Those with obvious surgical contraindications such as renal and cardiopulmonary failure, or those are not suitable for participating in this trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival;?????;liver function after surgery;Hospital stay; | — |
Countries
China
Contacts
Eastern Hepatobiliary Surgery Hospital, Second Military Medical University