Heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18 to 80 years; 2. Sinus rhythm, complete LBBB meeting Strauss’s standard definition; 3. Left ventricular ejection Fraction 1 year; 5. The residence is stable and can meet the requirements of follow-up during the study period.
Exclusion criteria
Exclusion criteria: 1. decline to participate or refuse to sign the written informed consent; 2. pregnant or planning to become pregnant; 3. participate in other clinical studies; 4. patients with mechanical tricuspid valve implantation; 5. persistent or permanent atrial fibrillation; 6. heart transplant patients or patients waiting for heart transplantation; 7. Patients with severe renal dysfunction of blood creatinine>2.5mg/dl or>275umol/L or glomerular filtration rate <= 30 ml/min/1.72m^2 within 30 days prior to enrollment; (9) Patients with severe liver dysfunction of liver function exceeding three times the upper limit of normal values in the five liver function items within 30 days before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite outcome of all-cause mortality and heart failure hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome of all-cause mortality;Outcome of heart failure hospitalization;Echocardiographic response/super-response rate; | — |
Countries
China
Contacts
Zhongshan Hospital, Fudan University