Bradycardia
Conditions
Interventions
Group 2:right ventricular pacing
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Signed informed consent form. 2. Aged >= 18 years. 3. Expected survival > 1 year. 4. Planned implantation or replacement of a single- or dual-chamber permanent pacemaker. 5. Anticipated ventricular pacing dependence (VP% > 40%), indicated by: grade II or high or III atrioventricular block (AVB); or persistent or permanent atrial fibrillation with slow ventricular response (mean ventricular rate 150 ms. 7. Stable residence and ability to comply with follow-up requirements during the study period.
Exclusion criteria
Exclusion criteria: 1. Women of childbearing age who are pregnant or intend to become pregnant during the study; 2. Participation in other clinical trials; 3. Patients with mechanical tricuspid valve implantation; 4. Secondary cardiomyopathy, such as amyloid sarcoidosis, hemochromatosis, glycogen storage disease and other diseases that affect the results of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite outcome of all-cause mortality, heart failure hospitalization, and pacing-induced cardiomyopathy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome of all-cause mortality;Outcome of heart failure hospitalization;Outcome of pacing-induced cardiomyopathy;Echocardiography;New York Heart Association (NYHA) functional class; | — |
Countries
China
Contacts
Public ContactXueying Chen
Zhongshan Hospital, Fudan University
Outcome results
None listed