asthma
Conditions
Interventions
case series:Nil
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) The subjects volunteered to participate in the study and strictly abide by the research regulations, understand and comply with the corresponding inspection, comply with the dosage and follow-up plan, and voluntarily sign the written informed consent; 2) They are 14-80 years old, regardless of gender and race; 3) Wheezing, shortness of breath, chest tightness or cough recurrently; 4) Wheezing was heard in both lungs; 5) The above symptoms can be relieved by themselves or after treatment; 6) Except wheezing, shortness of breath, chest tightness or cough caused by other diseases; 7) Patients with atypical symptoms should have at least one of the following tests positive: (1) Bronchial provocation test was positive; (2) FEV1 increased by more than 12% and the absolute value of FEV1 increase was more than 200 ml; (3) The diurnal variation rate of peak expiratory flow (PEF) within one week was more than 10%. Those who meet the above 7 items will be selected.
Exclusion criteria
Exclusion criteria: 1) Those who cannot cooperate with related inspections of this project or cannot cooperate for other reasons; 2) With COPD, interstitial pneumonia, active tuberculosis, community-acquired pneumonia, lung cancer, bronchiectasis, pulmonary heart disease, pulmonary embolism; combined with diseases of other systems (coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease); 3) Alcohol or narcotic drug abuse, history of drug abuse, or history of mental illness (such as schizophrenia, obsessive-compulsive disorder, depression), confrontational personality, bad motivation, suspiciousness or other emotional or intellectual problems, etc. may affect the effectiveness of the informed participation in this study Sexual situation; 4) Participating in other drug clinical trials, or stopping for less than 3 months; 5) Those with pregnancy; 6) Patients with obvious abnormalities in chest HRCT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| YKL-40; | — |
Countries
China
Contacts
Public ContactBenSuqin
Shanghai General Hospital
Outcome results
None listed