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The study of frontal-parietal rTMS on the mechanism of motor - cognitive function connectivity after stroke

The study of frontal-parietal rTMS on the mechanism of motor - cognitive function connectivity after stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036514
Enrollment
Unknown
Registered
2020-08-23
Start date
2020-08-21
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

control:rTMS False stimulation
cognitive:rTMS stimulating DLPFC
motor:rTMS stimulating M1
motor-cognitive :rTMS stimulating DLPFC and M1

Sponsors

The Fifth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of stroke made by the Fourth National Academic Conference on cerebrovascular diseases; 2. Patients with stroke confirmed by CT or MRI; 3. Patients with first stroke whose course of disease is more than 6 months; 4. Patients with or without hemiplegia of the left limbs and located in the right cerebral hemisphere; 5. Patients aged 30 to 75 years; 6. Patients with MMSE 10 to 24 points; 7. Hamilton Depression Scale (HAMD), HAMD =3; 9. At present, there are no outpatients who are in hospital for rehabilitation training and only receive drug treatment; 10. Patients who voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with frontal lobe injury; 2. Patients with contraindications to rTMS such as metal implants, pacemakers or skull defects; 3. Patients with previous history of brain tumor, brain trauma, epilepsy and seizure risk; 4. Patients with cognitive impairment before stroke; 5. Patients with any neuropsychiatric diseases and obvious emotional disorders that can affect the test results; 6. Patients with any other factors affecting the assessment and treatment.

Design outcomes

Primary

MeasureTime frame
gait analysis;functional near-infrared spectroscopy;Cognitive assessment;electromyogram analysis;Balance assessment;

Secondary

MeasureTime frame
Mini-mental State Examination;

Countries

China

Contacts

Public ContactQiang Lin

The Fifth Affiliated Hospital of Guangzhou Medical University

qianglin0925@gzhmu.edu.cn+86 18922497674

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026