Kawasaki Disease
Conditions
Interventions
Gold Standard:The diagnostic criteria established by the American Heart Association (AHA) as amended by the American Multidisciplinary Committee in 2017.
diagnosis 
and 
model 
of 
Kawasaki 
(Age, 
Sponsors
Shanghai Children's Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: All children met the diagnostic criteria established by the American Heart Association (AHA) as amended by the American Multidisciplinary Committee in 2017: 1. Fever lasts for 5 days or more, excluding other diseases with similar manifestations; 2. Extremities: Acute phase: erythema of palm (foot), finger (toe) end swelling; Convalescent period: 2 ~ 3 weeks occurrence finger (toe) nail edge desquamination; 3. Pleomorphic rash; 4. Both sides of the ball combined membrane hyperemia without secretions; 5. Changes in the lips and mouth: redness of the lips and mouth, chapped lips, diffuse congestion of the bayberry tongue, mouth and pharynx mucosa; Cervical lymph node lesions (diameter > 1.5 cm), usually unilateral; Inclusion criteria for the control group: Other febrile patients: meet one of the following conditions: 1. Fever for 3-5 days, 2. With a rash, cervical lymph node enlargement, hand and foot swelling, perianal flushing with one of the dandruff. 3. Blood routine examination indicated that CRP >= 30mg/L and erythrocyte sedimentation rate >= 40mm/h.
Exclusion criteria
Exclusion criteria: The body temperature can be reduced to normal after antibiotic use in patients with fever or respiratory infection who have been previously diagnosed with KD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| c reactive protein;white blood cell count;erythrocyte sedimentation rate;albumin;D - D dimer;cytokines;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactXie Lijian
Shanghai Children's Hospital
Outcome results
None listed