Type 2 diabetes
Conditions
Interventions
Intensive BP treatment and multifactorial management:Participants in the intensive BP treatment and multifactorial management group will be treated to a systolic BP target of <120 mmHg with glucose-lo
Standard BP treatment and multifactorial management:Participants in the standard BP treatment and multifactorial management group will be treated to a systolic BP target of <140 mmHg with glucose-lowe
Sponsors
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Men and women aged >= 60 years; (2) Type 2 diabetes (3) Raised systolic blood pressure:systolic blood pressure >= 140 mmHg on at least 1 anti-hypertensive medication; (4) Increased risk of cardiovascular disease: with history of cardiovascular disease, and/or subclinical cardiovascular disease, and/or eGFR 30-59 ml/min/1.73 m2; (5) Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Known secondary cause of hypertension; (2) One minute standing systolic BP 2.0 mg/dl; (9) Previous diagnosis of polycystic kidney disease or glomerulonephritis; (10) Any factors judged by the clinic team to be likely to limit adherence to interventions; (11) Currently participating in another intervention study; (12) Currently living with another participant; (13) Pregnancy, currently trying to become pregnant, or of child-bearing potential and not using birth control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major cardiovascular events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nonfatal myocardial infarction;Nonfatal stroke;Treated or hospitalized heart failure;Other acute coronary syndrome;Cardiovascular death; | — |
Countries
China
Contacts
Public ContactGuang Ning
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed