venous thromboembolism
Conditions
Interventions
Sponsors
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients are clearly pathologically diagnosed abdominal or pelvic malignant tumors (from general surgery department, gynecology department, urology department, etc.; including laparoscopic and open surgery); 2. Caprini score >=5 points; 3. Expecting life span >=6 months; 4. Patients need to receive routine VTE prophylaxis during hospitalization after operation (physical prevention and pharmaceutical prevention); 5. Tumor stage >=2.
Exclusion criteria
Exclusion criteria: 1. Catheter-related DVT; 2. Past history of VTE or vascular diseases, such as varicose veins and phlebitis; 3. Having received other surgical treatment in 6 months; 4. Clinical manifestations of complicating DVT/PE, but not comfirmed by imaging examination; 5. Past history of blood disorders or severe coagulation dysfunction; 6. Severe liver and renal dysfunction; 7. Long-term use of antithrombotic drugs before surgery; 8. Incomplete clinical data (diagnosis is not clear, medical history is incomplete, medication records are incomplete, etc.); 9. Presence of contraindications to heparin/anticoagulation, heparin allergy/HIT; 10. With heart failure, respiratory failure, refractory hypertension; 11. Pregnancy/lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VTE occurrence in the 4th week after operation;VTE occurrence in the 8th week after operation;all-cause mortality in the 4th week after operation;VTE occurrence in the 8th week after operation;all-cause mortality in the 4th week after operation;all-cause mortality in the 8th week after operation;duration from operation to VTE occurrence;bleeding events; | — |
Countries
China
Contacts
Public ContactYong Lu
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed