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Study on pain-related potentials and event-related potentials of recurrent transcranial magnetic stimulation combined with sertraline hydrochloride in the treatment for depressive disorder with somatic pain

Study on pain-related potentials and event-related potentials of recurrent transcranial magnetic stimulation combined with sertraline hydrochloride in the treatment for depressive disorder with somatic pain

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036464
Enrollment
Unknown
Registered
2020-08-23
Start date
2018-01-01
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major disorder depressive

Interventions

medicine group:Sertraline (75mg/d)

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 60 years old; 2. Right-handed; 3. In accordance with CCMD-3 for the diagnosis of persistent somatic pain disorders; 4. The numerical pain rating scale (NRS) score is greater than 4 points; 5. The course of disease is greater than 6 months; 6. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, brain, liver, and kidney dysfunction; 2. Patients with cerebral organic diseases (such as trauma, tumor, etc.); 3. Patients with peripheral nerve and muscular system lesions; 4. Patients suffering from other mental diseases; 5. Patients with history of mania or hypomania; 6. Patients with a history of alcohol abuse or psychoactive substance abuse; 7. Women during pregnancy or lactation; 8. Patients with visual and hearing impairments; 9. Any situation that cannot enter the high magnetic field environment (place a pacemaker, place a deep brain stimulator, place a vagal nerve stimulator, place a metal internal fixation device, etc.).

Design outcomes

Primary

MeasureTime frame
PRP;MMN;SG-P50;RMT;HAMD-24;NRS;TESS;P300;

Countries

China

Contacts

Public ContactZheng Zhong

West China Hospital, Sichuan University

zhengzhong1963@qq.com+86 18980601861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026