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Vaginal Lactobacillus capsule pretreatment improves FET outcomes in PCOS patients with dysbacteriosis: a multicenter randomized controlled trial

Vaginal Lactobacillus capsule pretreatment improves FET outcomes in PCOS patients with dysbacteriosis: a multicenter randomized controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036460
Enrollment
Unknown
Registered
2020-08-23
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Interventions

Vaginal flora intervention group:Living Preparation of Lactobacillus
Control group:Placebo

Sponsors

International Peace Marternity and Child Health Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Women aged 20-35 years with polycystic ovary syndrome; 2. Patients undergoing ivf-fet ;3. Rapid screening showed that lactobacilli belonged to the patients with the relative content less than 80%; 4. The subjects volunteered to join the study, signed the informed consent, and had good compliance, and cooperated with the follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients requiring antibiotics during the trial period; 2. Termination of ivf-fet for other reasons; 3. Patients who also participated in other clinical trials; 4. The investigator judged the patients who were not suitable for the study.

Design outcomes

Primary

MeasureTime frame
Pregnancy Rate;Implantation Rate;Live Birth Rate;

Secondary

MeasureTime frame
Pre-term Birth Rate;

Countries

China

Contacts

Public ContactHefeng Huang

International Peace Marternity and Child Health Hospital, Shanghai Jiao Tong University, Shanghai 200030, China

huanghefg@sjtu.edu.cn+86 180 1731 0186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026