Burning Mouth Syndrome
Conditions
Interventions
Experimental group:Jiawei Xiaoyao Tablets + Mikebao placebo
Control group:Jiawei Xiaoyao Tablets placebo + Mikebao
Sponsors
The Ninth People's Hospital affiliated to Shanghai Jiaotong University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years old; 2. Meet the diagnostic criteria of BMS defined by the International Association for The Study of Pain: (1) The symptoms lasted for more than 2 h per day for more than 3 months in total, and the pain was characterized by burning sensation and dry oral mucosa; (2) Normal appearance of oral mucosa and normal clinical examination; (3) There is no more suitable diagnosis in the Third edition of the International Classification of Headache Diseases. 4. In line with the syndrome of qi depression and fire clamps deficiency: irritable, or from night sweat, or headache, acerbity eyes, or cheeks, dry mouth, or irregular menstruation, lower abdomen pain, or urination pain, red tongue, thin yellow coating on the tongue, pulse string or deficiency; 5. Did not receive any treatment for BMS in 1 month; 6. VAS score (visual simulation score) is greater than or equal to 2; 7. Willing to sign written informed consent after full explanation.
Exclusion criteria
Exclusion criteria: 1. Other oral mucous membrane diseases; 2. Systemic diseases, such as diabetes, anemia, nutritional deficiencies (vitamins, folic acid, Fe, Zn, etc.), thyroid dysfunction, allergy to food or dental materials, autoimmune diseases, mental diseases, Sjogren's syndrome, etc.; 3. Bad oral habits such as biting cheek, tongue, etc.; 4. There are local stimulation factors, such as sharp tooth tip, bad repair, chemical and physical injury; 5. Does not conform to the liver depression fire clamp deficiency syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;Hamilton Anxiety Scale;Oral Health Impact Profile; | — |
Countries
China
Contacts
Public ContactHaiwen Zhou
The Ninth People's Hospital affiliated to Shanghai Jiaotong University Medical College
Outcome results
None listed