Upgraded development and clinical application of a new visualized ultra-low temperature and ultra-fast freeze-thaw instrument for human gametes

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000036430

Enrollment

Unknown

Registered

2020-08-23

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility preservation

Interventions

Sperm vitrification group:vitrification

Oocyte vitrification:vitrification

Vitrification of seminiferous tubules:vitrification

Vitrification of ovarian tissue:vitrification

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Obstructive azoospermia patients undergoing testicular biopsy, normal spermatogenesis, women of childbearing age between 18 and 38 years old, patients who donate ovarian tissue and eggs voluntarily.

Exclusion criteria

Exclusion criteria: Patients with non-obstructive azoospermia with abnormal spermatogenesis Patients with a history of endocrine diseases and hormone medications, chemotherapy and radiotherapy.

Design outcomes

Primary

Measure	Time frame
Sperm motility;Seminiferous tubule integrity;Oocyte microfilament distribution;Oocyte apoptosis;Granular cell apoptosis;Fertilization rate;Cleavage rate;	—

Countries

China

Contacts

Public ContactLi Zheng

Shanghai General Hospital

lizhengboshi@163.com+86 13564783816

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026