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A cross-sectional study for renal function of patients with chronic hepatitis B in China

A cross-sectional study for renal function of patients with chronic hepatitis B in China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036408
Enrollment
Unknown
Registered
2020-08-22
Start date
2020-08-21
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis B

Interventions

Case series:Nil

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with chronic hepatitis B who are older than 18 years old and younger than 75 years old; 2. Currently receiving nucleotide antiviral therapy; 3. Patients are willing to undergo laboratory tests related to renal function: renal function items include glomeruli Filtration rate (eGFR), urea nitrogen (BUN), blood creatinine, uric acid, beta 2 microglobulin, alpha 1 microglobulin and urine protein, etc.; 4. The patient is willing to undergo blood glucose testing; 5. The patients are informed and agree to participate in this session the study.

Exclusion criteria

Exclusion criteria: 1. Patients with decompensated liver cirrhosis; 2. Patients with HIV infection and malignant tumors; 3. Patients with severe mental illness or unable to cooperate; 4. Female patients during lactation and pregnancy; 5. Participation within three weeks or present Those who are participating in clinical research of other new drugs; 6. Those who cannot understand or express informed consent.

Design outcomes

Primary

MeasureTime frame
Blood Urea Nitrogen (BUN);Serum creatinine (Scr);Serum phosphorus;Serum calcium;Serum uric acid (UA);Blood glucose;Alanine aminotransferase (ALT);Aspartate aminotransferase (AST);Glutamyl transpeptidase (GGT);albumin (ALB);Serum potassium;alkaline phosphatase;Urine ß2 microglobulin (beta 2-MG);Urine a1 microglobulin (alpha1-MG);Retinol binding protein (RBP);Urine creatinine;Estimated glomerular filtration rate (eGFR);Urine Albumin;Urine Albumin/Urine Creatinine (ACR);Urine glucose;Urine red blood cells;24-hour urine protein quantification;Urine pH;Urine specific gravity;Acetyl-B-D-glucosaminidase (NAG);Urine potassium;Urine chloride;Urine sodium;Urinary calcium;Urine Leukocytes;Urine Phosphorus;Hepatitis B surface antigen (HBs Ag);Hepatitis B surface antibody (HBs Ab);Hepatitis B e surface antigen (HBe Ag);Hepatitis B e antibody (HBe Ab);Hepatitis B core antibody (HBcAb);Hepatitis B virus DNA quantification (HBV DNA);Liver imaging;—

Countries

China

Contacts

Public ContactChan Xie

The Third Affiliated Hospital of Sun Yat-sen University

happyxiechan@hotmail.com+86 13434383329

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026