liver space-occupying lesions
Conditions
Interventions
A:10 mmHg pneumoperitoneum pressure was used during the operation
B:The pneumoperitoneum pressure was 15mmHg
Sponsors
Zhongshan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged 18-75 years old; 2. Subjects with body mass index of 18.5 kg / m2-30 kg / m2; 3. Patients scheduled for laparoscopic liver resection.
Exclusion criteria
Exclusion criteria: 1. Patient with acute heart failure; 2. Patient with acute coronary insufficiency; 3. Patient with severe renal failure (defined as creatinine clearance < 30 mL/min or requiring renal replacement therapy); 4. Patient with preoperative shock (defined as the need for vasoactive drugs before surgery); 5. History of neuromuscular disease; 6. Contradiction to use TEE because of severe esophageal varices; 7. Participation in other drug trials in the 30 days prior to enrollment; 8. Parturient or breast-feeding women; 9. Inability to express oneself correctly, poor compliance, and inability to complete the test according to the study plan; 10. Patients or relatives refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intra cardiac gas embolism during operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| central venous pressure;Inferior vena cava collapse rate, IVCCR;Post-operative Quality of Recovery Scale, PQRS;Complications within 30 days after operation;Evaluation of surgeon satisfaction;Postoperative organ function;Intra-operative complication related to gas embolism;Number of hospital-free days at day 28;Need for unexpected intensive care unit admission or readmission;90-day survival;In-hospital survival; | — |
Countries
China
Contacts
Public ContactJing Zhong
Zhongshan Hospital Affiliated to Fudan University
Outcome results
None listed