Active bleeding and low platelet counts
Conditions
Interventions
Experimental group:Cryopreservation of platelets at 4 degrees C
control group:Platelets preserved at 22 degrees C
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Trauma and surgical bleeding are the main patients, aged 18 to 60 years old; (2) Patients with obstetric hemorrhage; (3) Voluntary signing of informed consent for transfusion and cryopreservation of platelets.
Exclusion criteria
Exclusion criteria: (1) Exclude patients with coagulation dysfunction caused by coagulation factor deficiency; (2) Patients taking antiplatelet drugs for a long time; (3) Patients with hypercoagulable diseases such as myocardial infarction and stroke; (4) Patients with severe multiple organ failure; (5) Patients with severe surgical trauma are expected to die within 24 hours; (6) Patients with postpartum hemorrhage complicated with severe liver and kidney failure; (7) The researcher thinks that it is not suitable for the patients; (8) Participants in other clinical trials; (9) Drug abuse, medical, psychological or social conditions that may interfere with the subjects' participation in research or evaluation of research results; (10) Epilepsy, dementia, or other spirits that need medical treatment cannot understand or comply with the research plan; (11) Patients with severe infectious diseases (incurable tuberculosis, pulmonary aspergillus) and aids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation index;Platelet number;wound drainage; | — |
Countries
China
Contacts
Public ContactJiangcun Yang
Department of Transfusion Medicine, Shaanxi Provincial People's Hospital
Outcome results
None listed