A preliminary prospective study based on non-invasive DNA content analysis to evaluate the risk of oral mucosal carcinogenesis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000036345

Enrollment

Unknown

Registered

2020-08-22

Start date

2020-10-01

Completion date

Unknown

Last updated

2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral potentially malignant disorders

Interventions

exposed group:NA

unexposed group:NA

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The clinical and pathological diagnosis was erythema, oral leukoplakia, oral lichen planus, oral lichenoid damage and oral submucosal fibrosis; 2. Aged between 18 and 75 years old; 3. Able to provide a history of bad habits such as smoking and drinking truthfully; 4. Able to cooperate with cell brush to sample exfoliated oral mucosa cells.

Exclusion criteria

Exclusion criteria: 1. The pathological diagnosis was cancer at the time of enrollment; 2. Carcinogenesis occurred within 6 months after enrollment; 3. Pregnant or lactating women; 4. Patients with other oral mucosal diseases and mental illnesses.

Design outcomes

Primary

Measure	Time frame
carcinogenesis;	—

Countries

China

Contacts

Public ContactLinjun Shi

Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine

191909117@qq.com+86 13917461596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026