Colorectal Cancer
Conditions
Sponsors
Cancer Hospital, Chinese Academy of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Adult males and females, aged between 18 to 75 years old; 2. Colonoscopy biopsy pathologically confirmed colorectal adenocarcinoma; 3. Preoperative colonoscopy or imaging diagnosis of tumor in the sigmoid colon or upper rectum; 4. The preoperative clinical diagnosis is T1-3NxM0; 5. The maximum diameter of the tumor diagnosed by preoperative imaging is not more than 5cm; 6. BMI<=30kg/m2; 7. No local complications before operation (no obstruction, incomplete obstruction, no massive active bleeding, no perforation, abscess formation, no local invasion); 8. The function of heart, lung, liver, kidney and bone marrow meets the requirements of surgery and anesthesia; 9. signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Past history of malignant colorectal tumors; 2) Simultaneous diagnosis of multiple primary colorectal tumors; 3) Preoperative imaging revealed cancerous nodules implanted; 4) There are contraindications to laparoscopic surgery, such as severe cardiopulmonary insufficiency; 5) Those who have undergone abdominal and pelvic surgery many times in the past or have extensive abdominal adhesions; 6) Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. who need emergency surgery; 7) The primary tumor invades the abdominal wall and/or adjacent organs, which makes R0 resection impossible; 8) Patients with familial adenomatous polyposis, Lynch syndrome-related cancer, and active inflammatory bowel disease; 9) Diagnosis of other malignant tumors in the past 5 years; 10) ASA grade >=grade IV and/or ECOG physical status score >=2 points; 11) Those with severe liver and kidney function, cardiopulmonary function, blood coagulation dysfunction, or combined with serious underlying diseases that cannot tolerate surgery; 12) Have a history of severe mental illness; 13) Pregnant or lactating women; 14) Those with uncontrolled infection before surgery; 15) Patients with other clinical and laboratory conditions considered by the researcher should not participate in the trial; 16) Those who have had anal disease causing abnormal anal function or anal stenosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year disease-free survival; | — |
Countries
China
Contacts
Public ContactXishan Wang
Cancer Hospital, Chinese Academy of Medical Science
Outcome results
None listed