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Combination of Xue-Sai-Tong and aspirin based on the antiplatelet effect and gastrointestinal injury

Combination of Xue-Sai-Tong and aspirin based on the antiplatelet effect and gastrointestinal injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036311
Enrollment
Unknown
Registered
2020-08-22
Start date
2020-10-31
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Group1:aspirin 100mg qd
Group 2:Xuesaitong 200mg tid
Group 3:aspirin 100mg qd+Xuesaitong200mg tid

Sponsors

Beijing University of Chinese Medicine, Dongzhimen hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 45 to 75 years; 2. meet the diagnostic criteria of CHD; 3. meet the diagnostic criteria of grade I–II angina according to the Canadian Cardiovascular Society (CCS); 4. meet the diagnostic criteria of blood stasis; 5. meet the diagnostic criteria of stable angina pectoris; 6. take regular aspirin for at least one month; 7. be informed of the study and voluntarily sign an informed consent.

Exclusion criteria

Exclusion criteria: 1. mental or physical disorders; 2. pregnant, breast-feeding, and menstruating women, as well as women planning pregnancy within three months; 3. severe heart disease(acute myocardial infarction or acute myocardial infarction in six months), severe cardiopulmonary dysfunction (e.g. cardiac function II); 4. severe primary diseases, such as liver and renal hematopoietic system damage, liver function (ALT>=2 ULN, AST>=2 ULN, kidney function, Cr> 1.0 ULN), or nervous and mental disorder; 5. poorly controlled hypertension (systolic pressure >160 mmHg; or diastolic pressure>100mmHg); 6. having participated in clinical trials in the last three months; 7. underwent surgery or had hemorrhagic tendency in the last eight weeks; 8. drug allergy history or with allergic constitution; 9. diabetes; 10. poor compliance or unsuitability for this clinical trial by investigators judgment.

Design outcomes

Primary

MeasureTime frame
occult fecal blood;calprotectin;platelet aggregation rate;PAC-1;P selectin;

Secondary

MeasureTime frame
I-FABP;P2Y12;

Countries

China

Contacts

Public ContactBaochen Zhu

Beijing University of Chinese Medicine, Dongzhimen Hospital

zbcbock123@sina.com+86 17710790716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026