Parkinson's Disease
Conditions
Interventions
TaiChi Group:TaiChi training
Brisk walking Group:Brisk walking training
Non-exercise control:No intervention
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) patients with primary Parkinson's disease who meet the clinical diagnostic criteria of MDS; 2) patients with early Parkinson's disease with H-Y stage 1-2.5; 3) Aged 50-70 years old; 4) Primary school grade 6 and above with educational attainment; 5) like sedentary lifestyle, no regular or regular exercise history in the past 2 years; 6) the drug treatment regimen remains stable for at least 3 months, and the treatment regimen remains unchanged during the follow-up period; 7) can walk or live independently; 8) willing to accept grouping, good compliance; 9) the MMSE score is greater than or equal to 24.
Exclusion criteria
Exclusion criteria: 1) participating in other drug clinical trials or other intervention studies, or participating in other exercise programs; 2) regular or regular exercise in the past 2 years; 3) fall in the past 6 months; 4) skeletal muscle disease or cardiopulmonary dysfunction; 5) illiteracy and dementia or MMSE score less than 24; 6) accompanied by severe depression or mental symptoms; 7) previous brain trauma or craniocerebral surgery; 8) complicated with other severe central nervous system lesions; 9) take drugs that affect the levels of blood sugar and blood lipids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The unified Parkinson's disease rating scale, UPDRS;Time Up and Go, TUG;Berg Balance Test, BBT;Parkinson's Disease Cognitive Rating Scale, PD-CRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3D gait analysis;Plasma metabonomics;Brain magnetic resonance imaging; | — |
Countries
China
Contacts
Public ContactPei Huang
Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed