Chronic obstructive pulmonary disease
Conditions
Interventions
Experimental group:Oxygen therapy with polymer oxygen humidification membrane
Control group:Oxygen therapy with ordinary oxygen humidification device
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years and <= 75 years, both male and female; 2. All patients met the diagnostic criteria of COPD in the gold guidelines 2020: after the application of bronchodilators, FEV1 / FVC < 70% indicated the existence of incomplete reversible airflow restriction. The percentage of FEV1 to the predicted value could be used to judge the degree of COPD airflow obstruction; 3. The symptoms of COPD patients were assessed according to the COPD assessment test (CAT) or the modified British Medical Research Council (MRC) dyspnea score. 4. Informed consent of patients.
Exclusion criteria
Exclusion criteria: 1. Patients with acute and chronic pain caused by lung cancer, pulmonary embolism, myocardial infarction, unstable angina pectoris, etc.; 2. Combined with bronchial asthma, pleural effusion or pneumatosis, heart failure and other sleep disorders; 3. Patients with sleep apnea syndrome or long-term use of hypnotic or sedative drugs; 4. Patients with anxiety, depression and mental system diseases, which affect communication and cognitive ability; 5. Patients with acute exacerbation complicated with respiratory failure were treated with ventilation; 6. The estimated survival time was less than 24 hours; 7. Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The cumulative oxygen inhalation time (hours) was recorded by camera in 14 days.; | — |
Secondary
| Measure | Time frame |
|---|---|
| PaO2 within 14 days;Length of stay;Critical illness rate and first aid rate; | — |
Countries
China
Contacts
Public ContactZhang Weixing
Shanghai General Hospital
Outcome results
None listed