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Clinical study of liquid biopsy based on cfDNA hydroxymethylation in the diagnosis of early stage gastrointestinal tumors

Clinical study of liquid biopsy based on cfDNA hydroxymethylation in the diagnosis of early stage gastrointestinal tumors

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036286
Enrollment
Unknown
Registered
2020-08-22
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal cancer of early stage

Interventions

Gold Standard:Pathological results
based&#32
on&#32
hydroxymethylation

Sponsors

Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.1 patients with early gastric cancer group: 1) The age is between 18 and 86 years old. 2) From October 2020, peripheral blood and remaining biopsy samples were collected from patients with high-grade intraepithelial neoplasia confirmed by biopsy pathology or received ESD or surgical treatment in our hospital. 1.2 non disease negative control group 1) The age is between 18 and 86 years old. 2) In normal physical examination patients, gastrointestinal endoscopy was performed in non cancer patients, and the physical examination results were basically normal.

Exclusion criteria

Exclusion criteria: 1) The patient's age, gender and other important personal information lost. 2) At the same time, patients with other tumors.

Design outcomes

Primary

MeasureTime frame
ROC curve;Sensitivity;specificity;

Countries

China

Contacts

Public ContactWenshuai Li

Huashan Hospital Affiliated to Fudan University

liwenshuai_1990@163.com+86 18818210729

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026