Skip to content

Validation of a dynamic risk predictive model for adverse events in patients with aortic dissection in real world data: a database-based non-randomized controlled clinical study

Validation of a dynamic risk predictive model for adverse events in patients with aortic dissection in real world data: a database-based non-randomized controlled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036276
Enrollment
Unknown
Registered
2020-08-22
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic dissection

Interventions

CDS group:This group received the real-time monitoring of dynamic risk predictive model, and carried out basic treatment under its guidance.
Traditional group:The dosage of antihypertensive drugs was adjusted when systolic blood pressure >120mmHg or systolic blood pressure 60bpm.

Sponsors

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: A. Patients with aortic dissection confirmed by CTA and/or MRI, including Stanford type A and B type dissection; B. Blood pressure and heart rate were recorded more than 6 times after admission; C. Patients over 18 years old, regardless of gender; D. Sign informed consent and agree to follow up regularly.

Exclusion criteria

Exclusion criteria: A. Aortic dissection resulting from other aortic diseases, such as an interaortic hematoma or a penetrating aortic ulcer; B. Traumatic aortic dissection; C. Aortic branch dissection; D. Aortic dissection with other diseases that seriously affect blood pressure and heart rate; E. Aortic association with pregnancy or lactation; F. Blood pressure and heart rate recorded less than 6 times after admission; G. Life expectancy less than 12 months; H. Subjects are allergic to antihypertensive drugs and contrast agents; I. Refuse to sign the informed consent, and fail to follow up as scheduled; J. Patients with antihypertensive drug contraindications.

Design outcomes

Primary

MeasureTime frame
adverse event;

Secondary

MeasureTime frame
All-cause mortality rate;Aortic dissection associated mortality;Aortic remodeling ratio;increment of cost and effective ratio;

Countries

China

Contacts

Public ContactXinwu Lu

Department of Vascular Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine

luxinwu@shsmu.edu.cn+86 13651839016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026