A prospective single-center study of transurethral high-power green laser vaporization enucleation of prostate

A prospective, randomized, single-center clinical study of transurethral high-power green laser vaporization of the prostate compared to transurethral resection of the prostate in the treatment of benign prostatic hyperplasia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000036273

Enrollment

Unknown

Registered

2020-08-22

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

benign prostatic hyperplasia

Interventions

GLEP:transurethral high-power green laser vaporization enucleation of the prostate

TURP:transurethral resection of the prostate

Eligibility

Sex/Gender

Male

Age

50 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Sign the informed consent; 2. Chinese males aged 50-100 (including 50 and 100 years old); 3. (1) Repeated urinary retention (at least one time after extubation can not urinate or two urinary retention); (2) Repeated hematuria, 5a-reductase inhibitor treatment is ineffective; (3) Repeated urinary tract infection with bladder stones ; (4) Secondary upper urinary tract hydrops (with or without renal impairment); (5) Combined with large diverticulum of bladder, inguinal hernia, severe hemorrhoids or prolapse.

Exclusion criteria

Exclusion criteria: 1. Diseases or conditions that affect patients' understanding, following and/or compliance with the research process; 2. Confirm one of the following conditions before surgery: (1) Qmax > 20ml/s; (2) Neurogenic bladder dysfunction; (3) History of lower urinary tract injury or previous prostate or urethral surgery; (4) Known Or intraoperatively confirmed tumor or prostate cancer; (5) Known or intraoperatively confirmed and complicated postoperative urethral stricture or bladder neck contracture; 3. Contraindications to other operations and anesthesia; 4. Other situations that the researcher considers inappropriate to participate in the research.

Design outcomes

Primary

Measure	Time frame
International Prostate Symptom Score in 1 month after surgery;Qmax;	—

Secondary

Measure	Time frame
PVR;QoL;	—

Countries

China

Contacts

Public ContactXin Xie

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

xx11149@rjh.com.cn+86 13916608990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026