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A prospective clinical study of PET-CT guiding postoperative cervical lymph node radiotherapy target planning for laryngopharyngeal squamous cell carcinoma

A prospective clinical study of PET-CT guiding postoperative cervical lymph node radiotherapy target planning for laryngopharyngeal squamous cell carcinoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036219
Enrollment
Unknown
Registered
2020-08-21
Start date
2020-11-01
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngopharyngeal squamous cell carcinoma

Interventions

single arm:PET-CT guiding postoperative cervical lymph node radiotherapy

Sponsors

Eye& ENT Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The age of the patient is 18-79 years old; (2) Pathologically diagnosed as laryngopharyngeal squamous cell carcinoma; (3) Karnofsky score >= 70 points, no serious medical complications; (4) Willing to receive surgical treatment, and the expected survival is not less than 6 months; (5) The enrolled patients also need to meet the following clinical laboratory standards: hemoglobin > 120 g/L. WBC is not less than 4 x 10^9/L and platelet is not less than 100x109/L. All indexes of liver and kidney function are within 1.25 times of the upper limit of normal; (6) Fully understand and agree to join the research, and sign an informed consent form; (7) There are follow-up conditions.

Exclusion criteria

Exclusion criteria: (1) Patients who refuse to undergo surgery for laryngopharyngeal squamous cell carcinoma; (2) Lymphatic drainage has been damaged by previous neck injuries, severe infections or other operations; (3) The diagnosis of the primary tumor is not clear; (4) Previously suffering from other malignant tumors or combined with a second primary tumor; (5) Those with severe comorbidities, including myocardial infarction, severe arrhythmia, severe cerebrovascular disease, ulcer disease, and mental illness.

Design outcomes

Primary

MeasureTime frame
Cervical lymph nodes;Overall survival rate;The rate of recurrence;

Secondary

MeasureTime frame
Quality of Life;

Countries

China

Contacts

Public Contactzhuyi

Eye & ENT Hospital, Fudan University

zhuyi1113@hotmail.com+86 13795411662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026