Alcohol dependence
Conditions
Interventions
Gabapentin Group:Taking gabapentin
SSRIs Group:Taking SSRIs
Valproate Group:Taking Valproate
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University
Eligibility
Sex/Gender
Male
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects who meet the diagnostic criteria of alcohol dependence in ICD-10 and dsm-5; 2. Male, aged 20-60, Han nationality, junior high school or above.
Exclusion criteria
Exclusion criteria: 1. Patients with previous history of gabapentin allergy or allergic reaction during treatment; 2. Patients with other major body diseases or severe liver and kidney injury; 3. Patients with history of other psychoactive substance abuse (except tobacco); 4. Patients with other psychiatric diseases and symptoms; 5. Patients with epileptic seizure history; 6. Subjects with history of craniocerebral trauma and coma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinic Institute Alcohol Withdrawal Syndrome Scale, CIWA-Ar;Penn Alcohol Craving Scale, PACS;Hamilton Anxiety Scale, HAMA;Hamilton Depression Scale, HAMD;Pittsburgh Sleep Quality Index, PSQI;Epworth Sleepiness Score, ESS;Mini Mental State Examination, MMSE;Trail Making Test B, TMT-B;Digital Span Test, DST;Verbal Fluency Test, VFT;Hopkins Verbol Learning Test-Revised, HVLT-R;Event-Related Potential, ERP ; | — |
Countries
China
Contacts
Public ContactWang Chuansheng
The Second Affiliated Hospital of Xinxiang Medical University
Outcome results
None listed