ossification of posterior longitudinal ligament
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Criteria for inclusion in the cervical posterior longitudinal ligament ossification group: 1. Single-segment or multi-segment ossification of the posterior longitudinal ligament of the cervical spine confirmed by CT three-dimensional reconstruction, or at least combined with two diseases of posterior longitudinal ligament ossification, ligamentum flavum ossification, and diffuse bone hyperplasia; 2. Between 18 and 75 years old, no gender limit; 3. Symptoms of spinal cord or nerve root compression, surgical indications and the patient's willingness to operate; 4. Willing to sign informed consent. Criteria for inclusion in the cervical posterior longitudinal ligament without ossification group: 1. No posterior longitudinal ligament ossification of the spine; only degeneration and herniated intervertebral disc; 2. Between 18 and 75 years old, no gender limit; 3. Symptoms of spinal cord or nerve root compression, surgical indications and the patient's willingness to operate; 4. Willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with uncontrolled hypertension, diabetes or other severe heart and lung diseases and other surgical contraindications; 2. Very poor coagulation function, platelets lower than 20 * 10^9/L or INR >= 3.5; 3. Patients diagnosed or suspected of having malignant tumor; 4. Pregnant and lactating women or women whose pregnancy is not excluded; 5. Patients suffering from mental illness; 6. Other researchers think it is not suitable for participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunohistochemical staining results; | — |
Countries
China
Contacts
Shanghai Changzheng Hospital