Coronary Heart Disease
Conditions
Interventions
Gold Standard:Fraction Flow Reserve (FFR)
Index test:Fast 
Computational 
Approach 
to 
Derive 
Flow 
Reserve 
From 
CT 
(CT-QFR), 
Quantitative 
(QFR).
Sponsors
Huadong Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Coronary CT angiography indicates that >= 1 stenosis with percent diameter stenosis between 30%-90% in a vessel >= 2mm. 2. The invasive coronary angiography should be less than 30 days after the coronary CT angiography.
Exclusion criteria
Exclusion criteria: 1. The target lesion has received coronary stent implantation or coronary artery bypass graft. 2. Renal function is seriously damaged (eGFR<30 ml/min/1.73m2). 3. Those who are contraindicated to use contrast agents, beta blockers, nitrates or adenosine drugs. 4. Acute myocardial infarction within 1 month. 5. The image quality of CTA or coronary angiography cannot be assessed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the degree of coronary stenosis measured by QCT;the degree of coronary stenosis measured by QCA;FFR value;QFR value;CT-QFR value;SEN, SPE, ACC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactXinkai Qu
Huadong Hospital
Outcome results
None listed