Preeclampsia
Conditions
Interventions
GroupA:placebo
GroupB:S - ketamine 0.025mg/kg
GroupC:S - ketamine 0.05mg/kg
GroupD:S - ketamine 0.125mg/kg
Sponsors
International Peace Maternal and Child Health Care Institute affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Pre-eclampsia patients aged 20-50 years; 2. ASA level 2~3; 3. Who are required to undergo cesarean section; 4. Patients requiring cesarean section.
Exclusion criteria
Exclusion criteria: 1. Maternal patients with contraindications to spinal anesthesia excluded; 2. Extreme obesity (BMI >= 32) and other pregnancy complications were excluded. 3. Alcohol, substance abuse and a history of mental illness; 4. Height less than 150cm, body mass greater than 100kg, gestational age less than 36 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vital signs;VAS scores;Sedation scores;Mental symptoms;Apgar scores;Fetal umbilical cord blood gas; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a, IL-6, IL-10; | — |
Countries
China
Contacts
Public ContactZeyong Yang
International Peace Maternal and Child Health care institute affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed