Sepsis
Conditions
Interventions
control group:placebo
Sponsors
Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The age of onset was between 18 and 80 years old; 2. The diagnostic criteria of 2016 international guidelines for severe sepsis and septic shock were met; 3. APACHE II score < 30; 4. They voluntarily participated in the experiment and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with allergy to traditional Chinese medicine and allergic constitution; 2. Patients with malignant tumor, liver cirrhosis, chronic renal failure (uremic stage), hematological diseases, HIV and other serious basic diseases were complicated; 3. Long term use of hormone, immunosuppressant and other drug treatment of patients; 4. Those who suffered from serious mental illness or were unable to cooperate with the trial; 5. Those who have participated in other clinical trials at the same time or within 30 days; 6. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| SOFA score;TCM syndrome score;tumor necrosis factor (TNF-a);C-reactive protein;procalcitonin;procalcitonin;interleukin-6;interleukin-10;fecal routine;species and quantity of intestinal microorganisms;superoxide dismutase;myocardial enzyme spectrum;troponin;liver function;kidney function;BNP;coagulation function;blood routine; | — |
Countries
China
Contacts
Public ContactFang Bangjiang
Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Outcome results
None listed