Clinical High Risk of Psychosis
Conditions
Interventions
CHR with single target TMS:single target TMS stimulation
CHR with two-target TMS:Two-target TMS intervention
CHR with deep TMS group:Deep TMS intervention
CHR with sham stimulation:Sham stimulation
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
All
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of "SIPS" and "SOPS": Agree to receive TMS treatment and sign informed consent; 2. The age range is 15-45 years old; 3. Intelligence quotient (IQ) > 69;
Exclusion criteria
Exclusion criteria: 1. Sensory/motion disorders(e.g., hearing disorders, blindness), neurological illness(brain injury, epilepsy), or other severe somatic illness which can lead to clinical high-risk symptoms; 2. Claustrophobia; 3. with meeallic objects in their head or any type of stimulation in their body; 4. DSM-V drug or alcohol dependence in recent three months; 5. DSM-V axis I mental disorder or corresponding past history; 6. At the time of enrollment, he/she had received any psychiatric medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the score of SIPS/SOPS;MCCB scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| the negative symptom scores of SIPS/SOPS;GAF scores;the coversion rate from CHR to Schizophrenia;Hippocampus - whole brain functional connectivity; | — |
Countries
China
Contacts
Public ContactJijun Wang
Shanghai Mental Health Center
Outcome results
None listed