Papulopustular rosacea
Conditions
Interventions
Doxycycline group:Oral doxycycline
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1) Male or female aged 18-65 years without cognitive impairment; 2) Diagnosed as papularpustular rosacea (Fitzpatrick skin type III-IV); 3) After giving full explanation to the purpose and content of this clinical trial (including the subjects' compliance, etc.), patients are volunteered to sign the informed consent and participate in the clinical trial on the basis of full understanding.
Exclusion criteria
Exclusion criteria: 1) Those who are known to be allergic to experimental drugs or related drugs; 2) Those who have received treatments (ALA-PDT, antibiotics, etc.) that affect the prognosis of rosacea within 2 months before entering the group; 3) Those who take phototoxic or photosensitive drugs within 8 weeks before entering the group (such as sulfonamides, phenothiazines, etc.); 4) Patients with facial diseases that may affect the evaluation of curative effect (skin photosensitivity, porphyria, other photodermatosis, etc.); 5) Participate in any drug clinical trial within 1 month before this trial (as subjects) ; 6) Complicated with serious diseases, including severe heart disease, cerebrovascular disease, uncontrolled diabetes, uncontrolled hypertension, etc; 7) Patients with abnormal liver function, dyslipidemia or severe low immunity ; 8) Patients with scar constitution; 9) Pregnant or lactating women, and subjects of childbearing age (including men) who refused to take appropriate contraceptive measures during the study; 10) Patients with severe physical or mental diseases that may affect treatment, evaluation, or poor compliance with the study program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of papularpustular lesions at 3 months after treatment.;Rosacea symptom and sign score.;Incidence of side effects.;Recurrence rate; | — |
Countries
China
Contacts
Public ContactLei Shi
Shanghai Dermatology Hospital
Outcome results
None listed