Rheumatoid arthritis
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for RA; Meet the diagnostic criteria for active RA. 2. Aged 18-75 years with a course of disease less than 1 year. 3. Disease Activity Score in 28 joints-Erythrocyte Sedimentation Rate (DAS28-ESR) >= 2.6 (rounded to 1 decimal place). 4. Patients receiving NSAIDs and hormone therapy were given a stable dose for at least 30 days before entering the trial, and remained the same for the rest of the treatment. 5. Patients receiving other DMARDs must be interrupted for at least 30 days before entering the trial.
Exclusion criteria
Exclusion criteria: 1. Patients with interstitial lung disease; Accompanied by severe elevations of liver enzymes. 2. Women who are pregnant, breast-feeding or who have recently prepared for childbirth. 3. Persons who are allergic or sensitized to the test drugs. 4. Patients with severe primary diseases of the heart, liver, kidneys, brain, endocrine system and hematopoietic system, psychiatric disorders, etc. 5. At the same time with other rheumatic diseases such as systemic lupus erythematosus, Sjogren's syndrome, myositis and so on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DAS28;Joint swelling count;Joint tenderness count;VAS;Evaluation of TCM syndrome curative effect;routine blood test;ESR;CRP;US7; | — |
Secondary
| Measure | Time frame |
|---|---|
| MMP3;TIMP;sCD14;CD14+; | — |
Countries
China
Contacts
Public ContactYang Guanghui
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed