Thoracic tumor
Conditions
Interventions
Ultrasound-guided paravertebral block -- simple ropivacaine group (PVB group):Before surgery, ultrasound guided paravertebral block was performed at two points T4 and T6, and a total of 20ml of 0.5% r
Ultrasound-guided thoracic erector spinae plane block -- simple ropivacaine group (ESPB group):Before the operation, ultrasound - guided erectro spinae plane block was performed at the T5 level. A tot
Ultrasound-guided intercostal nerve block-simple ropivacaine group (INB group):Preoperative intercostal nerve block was performed between T4, T5 and T6, and a total of 20ml of 0.5% ropivacaine was use
Ultrasound-guided epidural block-simple ropivacaine group (EB group):Preoperative epidural anesthesia was performed at the T5 level. After the experimental dose of 1% lidocaine was no problem, a total
Ultrasound-guided paravertebral block -- ropivacaine + dexmedetomidine group (VB-Dexm group):Before surgery, ultrasound-guided paravertebral block was performed at two points T4 and T6, and 0.5% ropiv
Ultrasound-guided thoracic erector spinae plane block of -- Ropivacaine + dexmedetomidine group (ESPB-Dexm group):Before surgery, ultrasound guided erectro spinae plane block was performed at the T5 l
Ultrasound-guided intercostal nerve block-Ropivacaine + dexmedetomidine group (InB-Dexm group):Preoperative intercostal nerve block was performed between T4, T5 and T6, and 0.5% ropivacaine and dexmed
Ultrasound-guided epidural block-Ropivacaine + dexmedetomidine (EB-Dexm group):Preoperative epidural
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 20-65, the American society of anesthesiologists class I ~ II, body mass index (bmi) 18 to 25 kg/m2.
Exclusion criteria
Exclusion criteria: (1) Preoperative anemia: Male Hb 37.5 degrees C one day before surgery; (3) Patients with pulmonary ventilation dysfunction before surgery; (4) Preoperative pulmonary infection, bronchial asthma or airway hyperresponsiveness; (5) Previous history of thoracic surgery; (6) Cardiac function level II or above; (7) Preoperative systolic blood pressure > 140 mmHg and/or diastolic blood pressure of > 90 mmHg in patients with hypertension; (8) Patients with congenital heart disease, valvular disease, coronary heart disease and arrhythmia before surgery; (9) Disease of central nervous system, history of stroke; (10) Combined with liver and renal insufficiency; (11) History of preoperative radiotherapy and chemotherapy; (12) Preoperative history of long-term chronic pain; (13) Patients who have taken analgesic drugs within 3 months before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative acute pain;Incidence of postoperative chronic pain;Preoperative, intraoperative, and postoperative inflammatory factor levels;Preoperative, intraoperative and postoperative immunological indexes; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total dose of opioids used by patients during the perioperative period;SpO2, heart rate, systolic blood pressure and diastolic blood pressure perioperatively;Incidence of postoperative nausea and vomiting;Postoperative quality of life; | — |
Countries
China
Contacts
Public ContactQiang Wang
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed