pancreaticoduodenectomy
Conditions
Interventions
experimental group:duct-to-mucosa combining back-to-back” cross horizontal mattress anastomosis
control group:single layer insertion anastomosis
Sponsors
Zhongshan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Informed consent is signed; (2) Aged 18-80 years; (3) Preoperative imaging examination suggested periampullary lesions, pancreatic head lesions or other lesions indicated by pancreaticoduodenectomy.
Exclusion criteria
Exclusion criteria: (1) Patients with severe heart and lung diseases who cannot tolerate pancreaticoduodenectomy or have other contraindications for pancreaticoduodenectomy; (2) Preoperative hemoglobin < 70g/L or albumin < 30g/L; (3) Those who have had organ transplant operation in the past and take immunosuppressive drugs; (4) those taking hormones, immunosuppressants or chemotherapy; (5) Persons with known HIV infection; (6) Suspicion of non-compliance or non-cooperation; (7) Crohn's disease; (8) The investigator believes that the subject has a mental disability or other defect that may prevent him from participating in the study; (9) Intraoperative exploration revealed that the tumor could not be resected or complicated with acute pancreatitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Humoral amylase;pancreatic fistula; | — |
Secondary
| Measure | Time frame |
|---|---|
| biliary fistula;delayed gastric emptying;Chylous fistula;LOS;time for anastomosis;drainage volume; | — |
Countries
China
Contacts
Public ContactZhang Lei
Zhongshan Hospital Fudan University
Outcome results
None listed