Neurofibromatosis type 2
Conditions
Interventions
3:Cochlear implant
2:Treatment of Avastin
1:follow-up observation
Sponsors
Ninth Perople's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. The clinically diagnosed patients with neurofibromatosis type 2 (NF2) and their family members who have obtained understanding through the education and education, all participants need to sign informed consent. 2. The age at diagnosis of NF2 is >= 3 years old.
Exclusion criteria
Exclusion criteria: (1) Inability to have full civil liability due to mental state; (2) According to clinical guidelines, neoadjuvant treatment must be performed before tumor tissue can be obtained by puncture or surgery; (3) Virus infection such as HIV, syphilis, gonorrhea; (4) Infections, mental disorders and other diseases in the ongoing or active period; (5) Currently participating in other drug intervention research clinical trials; (6) Are currently using anticoagulants (excluding contraceptives), have a history of bleeding or coagulation disorders; (7) Imaging shows hemorrhage within 6 months, or history of symptomatic intracranial hemorrhage, or any history of spontaneous intracranial hemorrhage; (8) Have autoimmune coagulopathy, including idiopathic thrombocytopenic purpura, etc.; (9) Those who cannot be followed up and evaluated as required; (10) Transplant recipient patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of tumor;Hearing evaluation; | — |
Countries
China
Contacts
Public ContactWang Zhaoyan
Ninth Perople's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed