mutiple myeloma
Conditions
Interventions
case series:N/A
Sponsors
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Eligible candidates are male or female adults aging from 18 to 75, and should have measurable symptomatic NDMM according to NCCN guideline (Multiple myeloma, 2020. V4). Patients should be CD38 positive validated by flow cytometry or immunohistochemical. 2) Patients should have at least one neoplastic lesion reflected by CT, MRI, or 18F-FDG PET/CT scan within 60 days upon registration; 3) Patients are willing to and capable of meeting our interview demands (including blood test and bone marrow biopsy); 4) Each candidate should have an Eastern Cooperative Oncology Group performance status score of 0 to 2 (on a 5-point scale, with higher numbers indicating greater disability).
Exclusion criteria
Exclusion criteria: 1) Patients with life expectancies less than 3 months; 2) Patients who are pregnant, under lactation, or are preparing for pregnancy; 3) Patients who are unable to accept PET/CT scan due to weight limitations; 4) Patients who had been diagnosed as other type of cancer before; 5) Patients who are allergic to humanized antibodies or get grade 3/4 adverse events during DARA treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CR; | — |
Countries
China
Contacts
Public ContactJian Hou
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed