hepatocellular carcinoma
Conditions
Interventions
Sponsors
Guangxi Medical University Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years old; 2. Primary resectable liver cancer patients combined with TYPE II-III PVTT (in line with EASL liver cancer diagnostic criteria in 2018); 3. Child-pugh level A in liver function; 4. ECOG PS 0; 5. Expected survival time more than 3 months; 6. ALT and AST no more than 3 ULN, platelet >=80x10~9 /L, creatinine less than 150 umol/L; 7. The patient and his/her authorized legal representative understand and agree to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Previous history of upper abdominal radiation therapy; 2) Child-pugh grade B or above in liver function; 3) Extrahepatic or regional lymph node metastasis; 4) There is contraindication to radiotherapy or TACE; 5) History of severe esophageal varices combined with bleeding or active gastrointestinal bleeding within 2 weeks of enrollment; 6) Pregnant or breastfeeding; 7) Had been treated with systemic chemotherapy, targeted or immunosuppressive drugs in the past 6 months; 8) Tumor rupture and hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OS;Cancer thrombotic downstaging rate;complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS;R0 resection rate; | — |
Countries
China
Contacts
Public ContactTING-SHI SU
Guangxi Medical University Cancer Hospital
Outcome results
None listed