Acute Lymphoblastic Leukemia
Conditions
Interventions
prednisone : prednisone
Sponsors
Shanghai Jiaotong university school of medicine affiliated Shanghai children's medical center
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Aged 1 month to 18 years; 2. Diagnosis of acute lymphoblastic leukemia by bone marrow morphology; 3. Diagnosis of ALL by immunophenotyping.
Exclusion criteria
Exclusion criteria: 1. sIgM+; 2. Acute leukemias of ambiguous lineage diagnosed according to WHO or EGIL criteria; 3. ALL evolved from chronic myeloid leukemia (CML); 4. Down's syndrome, or major congenital or hereditary disease with organ dysfunction; 5. Secondary leukemia; 6. Known underlying congenital immunodeficiency or metabolic disease; 7. Congenital heart disease with cardiac insufficiency; 8. Treated with glucocorticoids for >=14 days, or ABL kinase inhibitors for > 7 days within one month before enrollment, or any chemotherapy or radiotherapy within 3 months before enrollment (except for emergency radiotherapy to relieve airway compression); 9. Low risk patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OS;relapse CIN; | — |
Countries
China
Contacts
Public ContactShuhong Shen
Shanghai Children's Medical Center
Outcome results
None listed