Normal healthy people and people with peripheral vestibular dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for normal persons: 1. Healthy young volunteers aged 18 to 50 years old; 2. Chinese citizens; 3. All informed consent. Inclusion criteria for people with vestibular dysfunction: 1. Chinese citizens; 2. patients with peripheral vestibular dysfunction disease as the case group; 3. Under 50 years of age, the diseases include Menieres disease, sudden deafness with vertigo, Acoustic neuroma, vestibular neuritis, auditory neuropathy and otitis media patients were included and screened according to the guidelines; 4. Agree to participate in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria for normal population: 1. People with a history of deafness, ear disease, ear discharge or vertigo, and other neurological, intracranial, autoimmune and other systemic diseases; 2. Otoscope, audiometery, acoustic immittance test for any abnormality. Exclusion criteria for people with vestibular dysfunction: With non-peripheral vestibular dysfunction disease, accompanied by impaired central vestibular function, intracranial injury, mass, tumor, infarction, Those with multiple systemic diseases or those with central disease in related examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| p1 latency;n1 latency;threshold;SEN, SPE, ACC, AUC of ROC, Kappa; | — |
Secondary
| Measure | Time frame |
|---|---|
| amplitude;Amplitude asymmetry ratio; | — |
Countries
China
Contacts
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine