Low Back Pain
Conditions
Interventions
Group 1:Non intervention
Group 2:Rehabilitation treatment
Group 3:drug therapy
Group 4:Rehabilitation therapy + drug therapy
Group 5:Traditional surgery
Group 6:Intelligent operation
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Normal population: (1) Aged 18-80 years old; (2) There was no history of spinal injury or surgery; (3) There was no spinal deformity or chronic paravertebral muscle disease; (4) There was no history of malignant tumor, cardiovascular and cerebrovascular diseases and other systemic diseases such as myasthenia gravis; (5) Able to stand and walk independently, willing to cooperate to complete the specified actions; (6) It can be checked for radioactivity. Conservative treatment: (1) Patients with low back pain who did not receive treatment; (2) It can tolerate the action required by the test; (3) No NSAIDs were taken within 10 days; (4) No allergy to celecoxib or any other component in the drug; (5) Agreed to participate in the trial. Surgical treatment: (1) Aged 18-80 years old; (2) Patients with open or minimally invasive X-ray fluoroscopy guidance were allowed to locate the surgical access within the pedicle; (3) Subjects who voluntarily participated and signed informed consent.
Exclusion criteria
Exclusion criteria: Normal population: (1) Other systemic diseases such as diabetes, myasthenia gravis, etc.; (2) Recent fever, or bowel or bladder dysfunction; (3) Unable to cooperate to complete all research steps; (4) Because X-ray may cause damage to the fetus, fertile women who plan pregnancy or suspected pregnancy are not allowed to participate in the test; (5) Radiation tests are not acceptable. Conservative treatment: (1) History of back surgery; (2) Spinal malignant tumor, infection, fracture, cauda equina syndrome or ankylosing spondylitis or other inflammatory diseases; spinal deformity, such as lumbar spondylolisthesis; (3) Other systemic diseases, such as diabetes and kidney disease; (4) Patients who have received lumbar muscle training in the past year; (5) Unable to cooperate to complete all research steps; (6) Patients with active peptic ulcer / bleeding; (7) Severe osteoporosis, hypertension, heart disease. Surgical treatment: (1) Metal allergy, allergic constitution or multiple drug allergy; (2) Women in pregnancy and lactation period; (3) Subjects with coagulation dysfunction; (4) Subjects who failed in the same segment of spinal surgery and needed a second operation; (5) Those who have been participating in clinical trials of other drugs, medical devices, etc. within the past 3 months; (6) The deformity of pedicle of vertebral arch was abnormal; (7) The researchers think it is not suitable to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Countries
China
Contacts
Public ContactLi-Ming Cheng
Shanghai Tongji Hospital
Outcome results
None listed