sinonasal squamous cell carcinoma
Conditions
Interventions
Group 2:definitive chemotherapy
Sponsors
Eye, Ear, Nose & Throat Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary participation and written informed consent; 2. Aged 18-70 years old, male or female; 3. Pathological proved primary sinonasal squamous cell carcinoma; 4. Clinical stage III-IVb, without distant metastasis; 5. Measurable tumor volume; 6. Karnofsky score >=70, expected survival time >=6 months; 7. Blood routine test, liver, renal function and heart function are tolerant to chemoradiotherapy; 8. No history of mental illness; no drug addiction; 9. Gestational age should take effective contraceptive measures; Patients with good compliance are expected.
Exclusion criteria
Exclusion criteria: 1. Patients with other malignant tumors; 2. Patients with a history of head and neck malignancy, unless they have not received radiotherapy and the disease has not progressed for more than 2 years; 3. Patients who have participated in other clinical trials within one month before the trial; 4. Patients with serious neurological or mental diseases; 5. Pregnant, lactating patients, patients in the reproductive period without taking effective contraceptive measures; 6. Persons without personal freedom or independent capacity for civil conduct7Patients is not suitable to participate evaluated by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;progression-free survival; | — |
Countries
China
Contacts
Public ContactXinmao Song
Eye, Ear, Nose & Throat Hospital of Fudan University
Outcome results
None listed